Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models #933983

Авторы:
;
Жанры:
Медицина. Здоровье; Фармакология. Фармакодинамика. Фармакокинетика
Агент:
John Wiley & Sons Limited (prof) EUR
Формат:
PDF книга
Объем:
319 стр
Язык:
английский
Правообладатель:
John Wiley & Sons Limited
Аннотация:

This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis. • Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects • Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model building process and applications of empirical Bayesian estimates in the drug development environment • Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control • Has datasets, programming code, and practice exercises with solutions, available on a supplementary website

Поделиться страницей